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Basic Research Journal of Medicine and Clinical Sciences ISSN 2315-6864 Vol. 6(8): Pp 90-92 October 2017

Copyright© 2017 Basic Research Journals

International Scientific Indexing lSI Impact Factor (0.836)


Short Communication


Intraarticular analgesia: comparing 50mg and 100mg of tramadol to morphine for analgesia after arthroscopic knee surgery


*Kharrat A, Cheikhrouhou Hichem, Fki M, Jarraya F, Kolsi H, Drira D, Karoui A


Department of Anesthesiology, Habib Bourguiba Hospital, Sfax, Tunisia


*Corresponding author email: aminekharrat99@gmail.com


Received 28 September, 2017; Accepted 06 October, 2017; Published 09 October, 2017




Introduction: Intra-articular analgesia is an effective technique for analgesia after arthroscopy of the knee. The aim of this study was to study the intraarticular analgesic effect of tramadol by comparing two doses (50mg and 100mg) with morphine. Materials and methods: Prospective randomized study. Informed consent, local medical ethics committee was given. 30 patients (ASA I, II) divided into three groups: Group (M): 5mg morphine intra-articular (20ml); Group (T50): 50mg Tramadol intra-articular (20ml); Group (T100): 100mg Tramadol intra-articular (20ml). The procedure was performed under general anesthesia in all patients. Morphine or tramadol were injected by the surgeon 10 min before the drop of the tourniquet and 15min before the declampation. Visual Analogue Scale (VAS), side effects and additional analgesic requirements were noted at 4, 8 and 24 h postoperatively. Results: The VAS scores were lower in patients in the group (T100) compared to patients in the (M) and (T50) groups. Patients in the group (T100) had fewer analgesics during the first 24 hours postoperatively compared to patients in the (M) and (T50) groups. Conclusion: In intra-articular analgesia, 50mg of tramadol were found to be as effective as 5mg of morphine by the same route. In our study we were able to obtain an improvement in the quality of the analgesia by increasing the dose to 100mg.


Keywords: Intraarticular, analgesia, tramadol, morphine


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Vol. 6 No 9

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