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Basic Research Journal of Medicine and Clinical Sciences ISSN 2315-6864 Vol. 3(12): Pp 123-126 December 2014

Copyright© 2014 Basic Research Journals

International Scientific Indexing lSI Impact Factor (0.683)



Short Communication


We should not underestimate Vitamin B12 and folic acid deficiencies in oldest old


Sema Akinci1, Kamile Silay2, Tuba Hacibekiroglu1, Arife Ulas3, Abdulkadir Basturk1, Sule Mine Bakanay1, Tekin Guney1, Muhammed Bulent Akinci3, Imdat Dilek4


1Ankara Ataturk Training and Research Hospital, Department of Hematology, Ankara/Turkey

2Yildirim Beyazit University, Department of Geriatrics, Ankara/Turkey

3Yildirim Beyazit University, Department of Oncology, Ankara/Turkey

4Yildirim Beyazit University, Department of Hematology, Ankara/Turkey.


*Corresponding author email: sbakinci@hotmail.com


Received 18 December, 2014; Accepted 23 December, 2014




Aim: It was aimed to investigate hemogram parameters, ferritin, vitamin B12 and folic acid levels of patients above age 80 who applied to the internal medicine outpatient clinic. Methods: Leukocyte, hemoglobin, platelet, ferritin, vitB12 and folic acid levels of total 200 patients (108 (54%) female and 92 (46%) male) age 80 and older were investigated retrospectively. Results: Out of 200 patients, 54 (27%) patients had normal hemogram. Hemoglobin levels of 58 (29%) cases were found normal, 138 (69%) were found low and 4 (2%) were found high. Leukocyte levels were normal in 144 (72%), leukopenia was detected in 28 (14%), and leukocytosis in 28 (14%) cases. Platelet levels of 129 (64.5%) cases were normal, 52 (26%) were assessed as thrombocytopenia and 19 (9.5%) as thrombocytosis. The deficiency anemia detected in 81 (58.7%) cases and the number of patients who has ferritin, vitB12 and folic acid deficiencies were 16 (19.7%), 27 (33.3%), and 19 (23.5%) respectively. Pancytopenia was detected in 18 (9%) patients and bicytopenia was detected in 30 (15%). Conclusion: The frequency of anemia is increased in the geriatrics population above age 80, deficiency anemia in particular. The present study is different from the literature since the most common deficiency was vitB12, following folic acid and iron deficiency. The importance of supportive treatment with vitB12 and folic acid replacement should not be underestimated in this population.


Keywords: elderly, blood count, ferritin, vitB12, folic acid deficiency


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J. Med. Clin. Sci.

Vol.3 No 12

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